Equipment Labs - analytics | Centrum NOVASOME

Equipment Labs - analytics

Morphologi G3 from Malvern

Particle size and shape analyser in the 0.5 – 1000 µm range

Mastersizer 2000 with Hydro 2000S and Scirocco 2000 dispersion units from Malvern

Particle size analyser with laser diffraction in the 0.02 – 2000 µm range with Hydro 2000S dispersion unit for “wet” measurements and Scirocco 2000 dispersion unit for “dry” measurements

Mastersizer 3000 with Hydro MV and Aero S dispersion units with low and high energy nozzle from Malvern

Particle size analyser with laser diffraction in the 0.01 – 3500 µm range with dispersion units Hydro MV for “wet” measurements and Aero S for “dry” measurements

Spraytec from Malvern

Particle size analyser for aerosols and sprays by laser diffraction method in the 0.1 – 900 µm range

Zetasizer Nano-ZS from Malvern

Dynamic Light Scattering (DLS) Analyzer for particle size, zeta potential and molecular weight in the 0.6 nm – 6 µm range

NOVA touch from Quantachrome Instruments

Gas sorption flow analyser for surface area and porosity analysis

Confocal Raman Microscope (CRM), Alpha 300R, from WITec

A chemical mapping system characterized by high speed, sensitivity and resolution. Allowing confocal microscopy analysis, surface topography analysis and Raman mapping in two and three dimensions.

X'Pert3 Powder X-ray diffractometer - XRPD, from Malvern Panalitycal

This measuring system is equipped with a copper lamp, a linear detector (PIXcel1D), thus significantly reducing the analysis time, also an autosampler allowing to automate a series of measurements. The diffractometer works in both the reflection and the transmission modes. It is possible to measure samples placed in a capillary (analysis of small and sensitive samples).

Thermogravimetric instrument- TGA, TGA2, from Mettler Toledo

Thermogravimetric analysis ranging from room temperature up to 1000° C. Measurements in nitrogen and oxygen atmospheres.

Differential Scanning Calorimeter (DSC) - DSC3 from Mettler Toledo

Measurements in the temperature range -50 – 500 °C (in nitrogen atmosphere). Possibility of a multi-segment measurement.

Aqualab Vapor Sorption Analyzer (VSA) from Decagon

Analysis of water activity and moisture sorption curves (DVS and DDI isotherms). Water activity measuring range 0.030-0.950 with an accuracy of ±0.005. Controlled measuring temperature range 15-60 °C (stability ±0.1 °C).

X-ray fluorescence spectrometer (EDXRF) - Epsilon 1 Pharma, from Malvern Panalitycal

Quantitative and qualitative analysis in the Na-Am range (excluding Al). Capacity to analyse solid, liquid and semi-liquid samples.

Tensiometer/Goniometer - DSA25, from Krüss GmbH

A system to analyze surface wetting kinetics and the disintegration mechanism of tablets.

Liquid Chromatograph (HPLC)-UltiMate 3000 HPLC, from Thermo Scientific

HPLC system – operating pressure range: up to 620 bar (9,000 psi), diode array spectophotometric detector (DAD), wavelength range: 190 – 800 nm, data collection frequency: 100 Hz,

Liquid Chromatograph (uHPLC) -UltiMate 3000 uHPLC, from Thermo Scientific

uHPLC system – equipped with an automatic valve allowing analysis from 6 different channels, operating pressure range: up to 1034 bar (15,000 psi), up to 12 chromatographic columns can be installed simultaneously, diode array spectrophotometric detector (DAD), wavelength range: 190 – 800 nm, data collection frequency: 200 Hz,

Liquid Chromatograph (HPLC) - 1200 Serie, from Agilent Technologies

HPLC system – operating pressure range: up to 400 bar (5,800 psi), UV-VIS spectrophotometric detector, diode array spectrophotometric detector (DAD), refractive index (RI), and fluorescence detection (FLD), laser light scattering detector (ELSD)

Gas Chromatograph (GC) with "Headspace" Phase Sampler (HS) - Agilent 6850 Series GC System, 7694E Headspace Sampler, from Agilent Technologies

Gas chromatography system equipped with a “Headspace” phase sampler – Carrier gas: nitrogen or helium, Flame Ionization Detector (FID) with Headspace-type phase sampler with simultaneous annealing of up to 6 samples

Instrument for testing the active ingredient’s type I and II release capacity - AT Xtend, from Sotax

Instrument for testing the release of active substance from medicinal products type I and II according to Ph. Eur. and USP, equipment: paddles and baskets, temperature range: up to +450C (accuracy +/- 0.50C), stirrer setting range: 25-250 rpm (accuracy +/- 1 rpm), number of dishes for release: 8, possibility to record the release process in all dishes, compliance with Ph. Eur.

Instrument for testing the release of active substance type IV - CE 7smart, from Sotax

Instrument for testing the release of active substance from medicinal products type IV according to Ph. Eur. and USP, equipped with automatic sample collector, working mode: open, work in the loop, equipment: Ø12mm cells, Ø22.6 mm cells, temperature range: up to +450C, range of flow rate of the medium: 1.5 – 35 mL/min, number of measuring cells: 7.

Automatic Titrator - T50, from Mettler Toledo

Automatic titrator for potentiometric titration, used for the determination of substance and water content by Karl-Fisher volumetric method, minimum volume to be dispensed: 0.5 µl for 10 ml burette (1/20 000 of the volume of the burette being used).

TSQ 9000 mass spectrometer coupled with a TRACE 1310 gas chromatograph with a TriPlus RSH autosampler, from Thermo Scientific

A triple quadrupole mass spectrometer with an EI ionization source in a “Headspace” gas chromatograph phase sampler (HS) and flame ionization detector (FID). Quantitative analysis and screening in complex matrices.

Instrument for testing release of active substances from chewing gums - ERWEKA DRT-3, from ERWEKA

Instrument for testing the release of substances from chewing gums, possibility of simultaneous testing of three test samples, working pressure range: 6-8 bar, number of cycles per minute: 20-60 cycles, volume of the medium: 20-70 ml, temperature range: +250C – 450C.

Product stability testing chambers - KBF 240 E1, KBF 240 E5, KBF 720, from Binder, and ICH 256 L, from Memmert

Climatic chambers for testing product stability:
1) photostability test – temp. 25°C, humidity: 60%RH, UV light exposure
2) accelerated test – temp. 40°C, humidiy: 75% RH
3) intermediate test 35°C, humidiy: 65% RH
4) ) long-term test – temp. 25°C, humidity: 60%RH

Instrument for measuring the disintegration time DisiTest 50 from Sotax

Instrument for measuring the disintegration time of medicinal products according to Ph. Eur. and USP, automatic detection of the end of measurement point.

Q-Exactive Focus mass spectrometer coupled with an HPLC 2D Ultimate 3000 RS liquid chromatograph, from Thermo Scientific

Spectrometer with interchangeable ionization sources: ESI and APCI and Orbitrap mass analyser. Possibility of sample introduction via a direct injection or a chromatographic system with analytes separation. Possibility of sample introduction via a direct injection or a chromatographic system with analytes separation. Identification of unknown chemical compounds, structure determination and quantitative analysis of selected analytes with <<1ppm precision>.

Franz diffusion chambers - from PermeGear

Thermostated set with vertical diffusion chambers to study the permeation and release of active substances from epidermal forms. Cell volume approx. 5 ml, possibility to perform tests with natural and synthetic membranes.

Instrument for releasing active substances from the epidermal forms using the Enhancer Cell technique - Release device VK 7010 with automatic sampling station VK 8000, from Varian

Instrument for testing the release of active substances from medicinal products, equipment: paddles and baskets and accessories for the release of active substances from epidermal forms by the Enhancer Cell technique, temperature range: up to +550C (accuracy +/- 0.20C), stirrer setting range: 10-250 rpm (accuracy +/- 1 rpm), number of release dishes: 8, possibility to programme for an automatic sampling collection, compliance with Ph. Eur. and USP requirements.

Cookie	Duration	Description
cookielawinfo-checkbox-analytics		This cookie is set by GDPR Cookie Consent plugin. The cookie is used to store the user consent for the cookies in the category "Analytics".
cookielawinfo-checkbox-necessary		This cookie is set by GDPR Cookie Consent plugin. The cookies is used to store the user consent for the cookies in the category "Necessary".

R&D services

Analytical studies

Technological tasks

GMP System

R&D services

Analytical studies

Technological tasks

GMP System